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KMID : 0615720110280050087
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Jouranl of Korean Acupuncture and Moxibustion society
2011 Volume.28 No. 5 p.87 ~ p.96
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Review of Moxibustion Treatment for Hypertension in Clinical Trials
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Liu Yan
Park Ji-Eun
Kim Ae-Ran
Jung Hee-Jung
Choi Sun-Mi
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Abstract
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Objectives: The aim of this study is to review clinical trials using moxibustion on hypertension and to assess their methodology and results.
Methods: Electronic literature searches for clinical trials (randomized trial, non-randomized trial, before-after study) of moxibustion were performed in nine electronic databases (four international databases and five Korean databases) and handsearch. English, Korean or Chinese articles were included. Laboratory or animal studies were excluded.
Results: A total of twelve studies met the inclusion criteria. Seven randomized controlled trial, three non-randomized trials and two before-after studies were included. Seven studies used direct moxibustion(two are scarring one) and five used indirect one. Five of twelve studies used moxibustion treatment just one time, except for that most frequency was once daily or 2-3 times per week for 1-2 months. Of ten randomized or non-randomized studies, three used antihypertension drug control and another three used waiting list control. Compare to baseline, change of blood pressure after moxibustion treatment was significant in all studies. However, the results of effect in blood pressure between moxibustion and controlled were not consistent. Methodological quality of clinical trials included in this review was low and has risk of bias, especially in blinding of parcitipant.
Conslusions: There are little high-quality clinical trials of moxibustion for hypertension. To evaluate the effect of moxibustion, more rigorous trials are warranted. Also, methodology of clinical trials have to be descripted in detail.
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KEYWORD
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hypertension, moxibustion, acupoint, clinical trial
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